|
Persistent cloaca
|
0.300 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Spatiotemporal distribution of caudal-type homeobox proteins during development of the hindgut and anorectum in human embryos.
|
27042391 |
2016 |
|
Colonic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity.
|
15215241 |
2004 |
|
Colonic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells.
|
17599044 |
2008 |
|
Colonic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors.
|
18187048 |
2008 |
|
Colonic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway.
|
12947088 |
2003 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
CDX2 seems to be a marker for cellular phenotype better than an indicator of the origin of adenocarcinomas.
|
15894926 |
2005 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
All breast, nonmucinous ovarian, and most endometrial and pancreatic adenocarcinomas showed no immunoreactivity for CDX2.
|
15722794 |
2005 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colon.
|
11733373 |
2001 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Does HepPar-1 immunoexpression have a role in differential diagnosis of periampullary cancer?
|
18038313 |
2008 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
CDX2 as a useful marker of colorectal adenocarcinoma metastases to lung in pre-operative biopsy specimens.
|
17549351 |
2007 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
Although there is immunophenotypic overlap, focal staining with CK20 together with diffuse CK7 and sometimes p16 positivity helps to distinguish intestinal types of cervical adenocarcinoma from involvement by a colorectal adenocarcinoma; CEA and CDX2 are of no value in this regard.
|
18156982 |
2008 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
The aims of the present study were 1) to compare the mRNA and protein expression of CDX-2 in biopsies obtained from patients with BE and normal squamous epithelium and 2) to study the effect of two different bile salts, ursodeoxycholic acid (UDCA) and deoxycholic acid (DCA), on the mRNA expression of CDX-2 and vascular endothelial growth factor (VEGF) in Barrett's the adenocarcinoma cell line (OE-33).
|
17852856 |
2007 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
Consistent with previous reports, CDX2 staining was observed in gastric adenocarcinomas (n=71), more commonly in the intestinal-type than the diffuse-type (28.9 vs 11.5%, P<0.05).
|
15205684 |
2004 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma.
|
15362373 |
2004 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
Significant correlations were found between claudin-2 and Cdx2 protein expression in dysplasia and intestine-type adenocarcinoma (r = 0.112, p < 0.05).
|
18500171 |
2007 |
|
Adenocarcinoma
|
0.100 |
AlteredExpression
|
group |
LHGDN |
There was no CDX2 protein expression in normal squamous esophagus, but moderate to strong protein expression was seen in all Barrett's tissues and in a majority of the dysplasia and adenocarcinoma cells.
|
16291394 |
2005 |
|
Adenocarcinoma
|
0.100 |
Biomarker
|
group |
LHGDN |
Our results indicate that cervical adenocarcinomas can show nuclear immunopositivity for CDX2 even in the absence of overt morphologic features of colorectal differentiation.
|
18753946 |
2008 |
|
Barrett Esophagus
|
0.100 |
Biomarker
|
disease |
LHGDN |
Cdx2 as a marker of epithelial intestinal differentiation in the esophagus.
|
14576477 |
2003 |
|
Barrett Esophagus
|
0.100 |
Biomarker
|
disease |
LHGDN |
Accordingly, Cdx2 immunostaining could help identify patients with Barrett's metaplasia in cases where no goblet cells are visible in biopsies from the columnar-lined esophagus.
|
15167938 |
2004 |
|
Leukemia, Myelocytic, Acute
|
0.100 |
AlteredExpression
|
disease |
LHGDN |
In an analysis of 115 patients with AML, expression levels of CDX2 were closely correlated with deregulated HOX gene expression.
|
17855634 |
2008 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
LHGDN |
CDX2 as a useful marker of colorectal adenocarcinoma metastases to lung in pre-operative biopsy specimens.
|
17549351 |
2007 |
|
Colorectal Neoplasms
|
0.080 |
AlteredExpression
|
group |
LHGDN |
Silencing of CDX2 expression in colon cancer via a dominant repression pathway.
|
12947088 |
2003 |
|
Colorectal Neoplasms
|
0.080 |
AlteredExpression
|
group |
LHGDN |
CDX-2 expression is reduced in colorectal carcinomas with solid growth pattern and proximal location, but is largely independent of MSI status.
|
15619975 |
2004 |
|
Colorectal Neoplasms
|
0.080 |
Biomarker
|
group |
LHGDN |
Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status.
|
18587323 |
2008 |
|
Colorectal Neoplasms
|
0.080 |
Biomarker
|
group |
LHGDN |
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.
|
15466189 |
2004 |